Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2894460 | 0.91 | USP2 (0.41) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL2892856 | 0.91 | USP2 (0.41) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL2894392 | 0.90 | MAPT (0.40) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL2896676 | 0.90 | MAPT (0.40) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL12564389 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2TGM2TSHRFOLH1 | |
| SCHEMBL2458918 | 0.86 | TGM2 (0.42) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL2891734 | 0.86 | TGM2 (0.42) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL2458923 | 0.86 | TGM2 (0.42) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL2888631 | 0.86 | TGM2 (0.42) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL865337 | 0.85 | ALDH1A1 (0.47) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477980-A1 | HCV PROTEASE INHIBITORS | Taigen Biotechnology Co., Ltd. (TW) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011034518-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2011-03-24 | — | — | WO | disclosed |