Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456933 | 0.93 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL14456910 | 0.90 | CYP3A4 (0.54) | CYP3A4 | |
| SCHEMBL14456915 | 0.90 | CYP3A4 (0.57) | CYP3A4 | |
| SCHEMBL18985960 | 0.88 | TBK1 (0.60) | CYP3A4TBK1 | |
| SCHEMBL14456935 | 0.88 | CYP3A4 (0.46) | CYP3A4 | |
| SCHEMBL14456916 | 0.87 | CYP3A4 (0.60) | CYP3A4 | |
| SCHEMBL14456936 | 0.86 | MEN1 (0.47) | CYP3A4 | |
| SCHEMBL14456931 | 0.86 | MEN1 (0.55) | CYP3A4 | |
| SCHEMBL14456932 | 0.86 | MEN1 (0.57) | CYP3A4TBK1 | |
| SCHEMBL14456898 | 0.85 | CYP3A4 (0.56) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |