Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456929 | 0.86 | MEN1 (0.51) | MEN1KMT2ACYP3A4SMN1; SMN2GAA | |
| SCHEMBL14456908 | 0.86 | CYP3A4 (0.54) | CYP3A4 | |
| SCHEMBL14469363 | 0.84 | CYP3A4 (0.48) | MEN1KMT2ACYP3A4SMN1; SMN2GAA | |
| SCHEMBL14456933 | 0.82 | CYP3A4 (0.55) | CYP3A4SMN1; SMN2 | |
| SCHEMBL14456938 | 0.79 | CYP3A4 (0.51) | CYP3A4 | |
| SCHEMBL14456910 | 0.79 | CYP3A4 (0.54) | MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL14456915 | 0.79 | CYP3A4 (0.57) | CYP3A4 | |
| SCHEMBL14456935 | 0.79 | CYP3A4 (0.46) | CYP3A4ALDH1A1 | |
| SCHEMBL18985960 | 0.77 | TBK1 (0.60) | CYP3A4 | |
| SCHEMBL14456916 | 0.76 | CYP3A4 (0.60) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |