Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456734 | 0.81 | KMT2A (0.51) | MEN1KMT2ANR4A1NR4A2NR4A3 | |
| SCHEMBL14456851 | 0.80 | KMT2A (0.58) | MEN1KMT2AATMCETPSLC6A4 | |
| SCHEMBL13876173 | 0.80 | TP53 (0.56) | RAF1TRPV1LMNA | |
| SCHEMBL5642804 | 0.79 | MEN1 (0.50) | MEN1KMT2ANR4A1NR4A2NR4A3 | |
| SCHEMBL5644342 | 0.75 | SLC6A2 (0.55) | MEN1KMT2AATMNR4A1NR4A2 | |
| SCHEMBL14457441 | 0.74 | MEN1 (0.46) | MEN1KMT2AATMNR4A2SLC6A4 | |
| SCHEMBL5642176 | 0.72 | ERCC1 (0.48) | MEN1KMT2ANR4A2SLC6A4NPC1 | |
| SCHEMBL4616603 | 0.71 | PPARA (0.65) | MEN1KMT2A | |
| SCHEMBL4742580 | 0.70 | AKR1C3 (0.70) | MEN1KMT2ANR4A2NPC1POLB | |
| SCHEMBL4616819 | 0.70 | PPARD (0.56) | MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098352-A2 | SUBSTITUTED PYRIDINEAMIDE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-30 | — | — | WO | disclosed |