Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644342 | 0.90 | SLC6A2 (0.55) | MEN1KMT2ASLC6A2SLC6A4ERCC1 | |
| SCHEMBL5642176 | 0.87 | ERCC1 (0.48) | MEN1KMT2ASLC6A2SLC6A4ERCC1 | |
| SCHEMBL5643090 | 0.83 | CRHBP (0.47) | MEN1KMT2AHPGDSLC6A2SLC6A4 | |
| SCHEMBL5643681 | 0.82 | ERCC1 (0.44) | MEN1KMT2ASLC6A2SLC6A4ERCC1 | |
| SCHEMBL5644680 | 0.82 | POLB (0.47) | MEN1KMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL14456734 | 0.81 | KMT2A (0.51) | MEN1KMT2AALDH1A1HPGDSLC6A2 | |
| SCHEMBL5644473 | 0.81 | RIPK1 (0.51) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL5644480 | 0.79 | KMT2A (0.79) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL14456958 | 0.79 | CRHBP (0.42) | MEN1KMT2AALDH1A1HPGDSLC6A2 | |
| SCHEMBL14456972 | 0.79 | MEN1 (0.55) | MEN1KMT2ASLC6A4NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |