Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456985 | 0.92 | CYP3A4 (0.56) | POLBCYP3A4ALDH1A1LMNATSHR | |
| SCHEMBL14456977 | 0.91 | POLB (0.56) | POLBCYP3A4ALDH1A1CNR1LMNA | |
| SCHEMBL14456996 | 0.91 | POLB (0.51) | POLBCYP3A4ALDH1A1CNR1LMNA | |
| SCHEMBL14456988 | 0.90 | CYP3A4 (0.54) | POLBCYP3A4TSHRKMT2A | |
| SCHEMBL14456976 | 0.87 | POLB (0.52) | POLBCYP3A4ALDH1A1CNR1LMNA | |
| SCHEMBL14457004 | 0.86 | ALDH1A1 (0.54) | POLBCYP3A4ALDH1A1LMNATSHR | |
| SCHEMBL14456975 | 0.86 | CNR1 (0.60) | POLBCYP3A4ALDH1A1CNR1LMNA | |
| SCHEMBL14456964 | 0.86 | CNR1 (0.60) | POLBCYP3A4ALDH1A1CNR1NPSR1 | |
| SCHEMBL14456949 | 0.85 | CYP3A4 (0.51) | POLBCYP3A4ALDH1A1TSHRKMT2A | |
| SCHEMBL14456992 | 0.85 | POLB (0.52) | POLBCYP3A4ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |