SCHEMBL14458059

SCHEMBL14458059

CC1=C[C@@H](C)CC(C)(C)C1=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731685 0.77 CYP3A4 (0.43) ABCB1
SCHEMBL3630532 0.77 CYP3A4 (0.43) ABCB1
SCHEMBL3150036 0.77 CYP3A4 (0.43) ABCB1
SCHEMBL11845051 0.71
SCHEMBL2184267 0.69 NFE2L2 (0.36)
SCHEMBL8442444 0.67
SCHEMBL14458084 0.65
SCHEMBL811287 0.62 NPC1 (0.33)
SCHEMBL3208597 0.62
SCHEMBL6192821 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247752-B2 Stereoselectively reducing 2,6,6-trimethyl-2-cyclohexene-1,4-dione with an optically active chiral catalyst to form an optically active hydroxycyclohexenone, contacting the product with a reducing agent to form an optically active diol, and using the diol to form astaxanthin CARDAX PHARMACEUTICALS, INC. (US) 2007-07-24 US disclosed