SCHEMBL3630532

SCHEMBL3630532

CC1=CC(O)CC(C)(C)C1=O

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.43
ABCB1 P08183 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3150036 1.00 CYP3A4 (0.43) CYP3A4ABCB1PTPN1
SCHEMBL8731685 1.00 CYP3A4 (0.43) CYP3A4ABCB1PTPN1
SCHEMBL14458059 0.77 ABCB1 (0.30) ABCB1
SCHEMBL19657437 0.75 CYP3A4 (0.36) CYP3A4
SCHEMBL11845051 0.73
SCHEMBL15908513 0.73
SCHEMBL7702140 0.71 ABCB1 (0.36) CYP3A4ABCB1
SCHEMBL11592365 0.71 ABCB1 (0.36) CYP3A4ABCB1
SCHEMBL11451525 0.67 CYP3A4 (0.31) CYP3A4
SCHEMBL7759177 0.67 ABCB1 (0.30) ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100041922-A1 METHOD FOR THE ENANTIOSELECTIVE PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-2,6,6-TRIMETHYL-CYCLOHEX-2-ENONE DERIVATIVES BASF SE (DE) 2010-02-18 US claimed
EP-0837060-B1 Preparation of an epoxide HOFFMANN LA ROCHE (CH) 2001-04-04 EP claimed
US-5919956-A Process for the C1 -homologization of protected phorenol ROCHE VITAMINS INC. (US) 1999-07-06 US claimed
EP-0837060-A1 Preparation of an epoxide F. HOFFMANN-LA ROCHE AG (CH) 1998-04-22 EP claimed
US-3989857-A Flavoring phenol or phenol derivative containing food or feed with cycloaliphatic derivatives FIRMENICH S.A. (CH) 1976-11-02 US claimed
JP-10120669-A None JP disclosed
US-10617144-B2 Molecularly imprinted polymers for treating tobacco material and filtering smoke from smoking articles R.J. REYNOLDS TOBACCO COMPANY (US) 2020-04-14 US disclosed
WO-2018114733-A1 PROCESS FOR THE PREPARATION OF STEREOISOMERIC PURE C9-ACETALS BASF SE (DE) 2018-06-28 WO disclosed
US-7858828-B2 Process for synthesis of (3R,3'R,6'R)-lutein and its stereoisomers UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2010-12-28 US disclosed
US-20100041922-A1 METHOD FOR THE ENANTIOSELECTIVE PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-2,6,6-TRIMETHYL-CYCLOHEX-2-ENONE DERIVATIVES BASF SE (DE) 2010-02-18 US disclosed
US-20100041922-A1 METHOD FOR THE ENANTIOSELECTIVE PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-2,6,6-TRIMETHYL-CYCLOHEX-2-ENONE DERIVATIVES BASF SE (DE) 2010-02-18 US disclosed
US-20100041922-A1 METHOD FOR THE ENANTIOSELECTIVE PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-2,6,6-TRIMETHYL-CYCLOHEX-2-ENONE DERIVATIVES BASF SE (DE) 2010-02-18 US disclosed
US-4029106-A TOBACCO, 3-ISOPROPYL-CYCLOPENT-2-EN-1-ONE FIRMENICH S.A. (CH) 1977-06-14 US disclosed
US-4029108-A TOBACCO FIRMENKH SA (CH) 1977-06-14 US disclosed
US-4014350-A CARYOPHYLLENE EPOXIDE AND ITS ALCOHOLS; FLAVORINGS FOR TOBACCO, FOODSTUFFS AND DRUGS FIRMENICH S.A. (CH) 1977-03-29 US disclosed
US-3989857-A Flavoring phenol or phenol derivative containing food or feed with cycloaliphatic derivatives FIRMENICH S.A. (CH) 1976-11-02 US disclosed
US-3983885-A AROMATIC COMPOSITIONS FIRMENICH S.A. (CH) 1976-10-05 US disclosed
US-3981311-A Aromatic compositions FIRMENICH S.A. (CH) 1976-09-21 US disclosed
US-3957061-A Aromatic compositions FIRMENICH S.A. (CH) 1976-05-18 US disclosed
US-3937228-A Aromatic compositions FIRMENICH SA (CH) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041922-A1 METHOD FOR THE ENANTIOSELECTIVE PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-2,6,6-TRIMETHYL-CYCLOHEX-2-ENONE DERIVATIVES CYP8B1, CYP51A1, HSD3B1 CYP3A4 45/4885ABCB1 3272/4885PTPN1 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.