Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002724 | 0.84 | MEN1 (0.68) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL14314684 | 0.81 | PKM (0.63) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL14314685 | 0.79 | PKM (0.65) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL18997840 | 0.77 | PKM (0.66) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL25944225 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL22604257 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL3919941 | 0.72 | PKM (0.68) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL4380434 | 0.72 | GAA (0.46) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL4390904 | 0.72 | GAA (0.46) | MEN1KMT2APOLBTSHRMAPK1 | |
| SCHEMBL4385434 | 0.72 | GAA (0.46) | MEN1KMT2APOLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241745-B2 | Pyridyl alkene and pyridyl alkine acid amides as cytostatics and immunosupressives | ASTELLAS PHARMA GMBH (DE) | 2007-07-10 | — | — | US | disclosed |