Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5619786 | 0.88 | MAPK14 (0.32) | GRM5MAPK14 | |
| SCHEMBL5619598 | 0.86 | GSK3A (0.41) | GCKGRM5MAPK14 | |
| SCHEMBL6165074 | 0.78 | MAPK14 (0.44) | GCKGRM5EP300CREBBPMAPK14 | |
| SCHEMBL5618849 | 0.78 | MAPK14 (0.38) | GCKGRM5RORCEP300CREBBP | |
| SCHEMBL7707024 | 0.77 | MAPK14 (0.39) | MAPK14 | |
| SCHEMBL14459299 | 0.77 | GCK (0.37) | GCKGRM5RORCEP300CREBBP | |
| SCHEMBL297067 | 0.76 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL6163971 | 0.75 | MAPK14 (0.51) | GCKGRM5RORCEP300CREBBP | |
| SCHEMBL6164680 | 0.75 | MAPK14 (0.43) | GCKEP300CREBBPMAPK14 | |
| SCHEMBL6574700 | 0.75 | MAPK14 (0.36) | GCKMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241758-B2 | Compounds useful as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-07-10 | — | — | US | disclosed |