Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 19/20 | 0.56 |
| ▸ | MPEG1 | Q2M385 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17123724 | 0.93 | MAPT (0.75) | ALDH1A1MAPTTHRBTDP1ALOX5 | |
| SCHEMBL14407319 | 0.87 | MAPT (0.68) | ALDH1A1MAPTTHRBTDP1ALOX5 | |
| SCHEMBL5146178 | 0.84 | MAPT (0.64) | ALDH1A1MAPTTHRBTDP1ALOX5 | |
| SCHEMBL5143424 | 0.84 | MAPT (0.64) | ALDH1A1MAPTTHRBTDP1ALOX5 | |
| SCHEMBL16465116 | 0.84 | MAPT (0.78) | ALDH1A1MAPTTHRBTDP1ALOX5 | |
| SCHEMBL16464673 | 0.84 | MAPT (0.78) | ALDH1A1MAPTTHRBTDP1ALOX5 | |
| SCHEMBL5588607 | 0.84 | ALOX5 (0.62) | ALDH1A1MAPTTHRBTDP1ALOX5 | |
| SCHEMBL9578637 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTTHRBTDP1ALOX5 | |
| SCHEMBL21026408 | 0.80 | MAPT (0.84) | ALDH1A1MAPTTHRBTDP1ALOX5 | |
| SCHEMBL11857681 | 0.79 | MAPT (0.96) | ALDH1A1MAPTTHRBTDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095631-A2 | NEW DRUG DELIVERY SYSTEM FOR CROSSING THE BLOOD BRAIN BARRIER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | WO | disclosed |