Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14459921 | 0.99 | NPC1 (0.51) | NPC1RAB9AGAAPDE10AHPGD | |
| SCHEMBL14459692 | 0.99 | NPC1 (0.54) | NPC1RAB9AGAAPDE10AHPGD | |
| SCHEMBL14459924 | 0.97 | NPC1 (0.53) | NPC1RAB9AGAAPDE10AHPGD | |
| SCHEMBL24063115 | 0.85 | NPC1 (0.60) | NPC1RAB9AGAAPDE10AHPGD | |
| SCHEMBL22649095 | 0.85 | NPC1 (0.67) | NPC1RAB9AGAAHPGDKDM4E | |
| SCHEMBL16002467 | 0.84 | NPC1 (0.51) | NPC1RAB9AGAAPDE10AHPGD | |
| SCHEMBL21769798 | 0.84 | NPC1 (0.48) | NPC1RAB9AGAAPDE10AHPGD | |
| SCHEMBL17755354 | 0.83 | NPC1 (0.55) | NPC1RAB9AGAAPDE10AHPGD | |
| SCHEMBL16281922 | 0.80 | NPC1 (0.66) | NPC1RAB9AGAAPDE10AHPGD | |
| SCHEMBL16000738 | 0.80 | NPC1 (0.70) | NPC1RAB9AGAAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070200490-A1 | Nitrogenous Heterocycle Derivative, And Organic Electroluminescent Element Employing The Same | IDEMITSU KASON CO.LTD (JP) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070200490-A1 | Nitrogenous Heterocycle Derivative, And Organic Electroluminescent Element Employing The Same | RPS3A, NCOA3, HNRNPA0 | NPC1 4031/4885RAB9A 779/4885GAA 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.