SCHEMBL22649095

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16281922	0.91	NPC1 (0.66)	NPC1RAB9AGAADGAT1KCNH2
	SCHEMBL417825	0.90	ALDH1A1 (0.71)	NPC1RAB9AGAAKDM4EALDH1A1
	SCHEMBL903717	0.89	NPC1 (0.66)	NPC1RAB9AGAADGAT1KCNH2
	SCHEMBL27825168	0.89	PRMT1 (0.54)	NPC1RAB9AGAADGAT1KCNH2
	SCHEMBL23131913	0.88	NPC1 (0.61)	NPC1RAB9AGAADGAT1KCNH2
	SCHEMBL10826401	0.88	KDM4E (0.72)	NPC1RAB9AGAAKDM4EALDH1A1
	SCHEMBL14459924	0.88	NPC1 (0.53)	NPC1RAB9AGAADGAT1KCNH2
	SCHEMBL7852530	0.88	NPC1 (0.71)	NPC1RAB9AGAAKDM4EALDH1A1
	SCHEMBL7659118	0.87	ALDH1A1 (0.54)	NPC1RAB9AGAADGAT1KCNH2
	SCHEMBL23131621	0.87	NPC1 (0.56)	NPC1RAB9AGAADGAT1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.