Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 9/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.49 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17755354 | 0.88 | NPC1 (0.55) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL14459921 | 0.86 | NPC1 (0.51) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL12887920 | 0.86 | NPC1 (0.63) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL16994454 | 0.86 | NPC1 (0.51) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL30293222 | 0.86 | NPC1 (0.51) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL14459924 | 0.85 | NPC1 (0.53) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL14459963 | 0.85 | NPC1 (0.53) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL14459692 | 0.83 | NPC1 (0.54) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL16994455 | 0.83 | RAB9A (0.49) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL16000738 | 0.83 | NPC1 (0.70) | NPC1RAB9AGAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3916823-A2 | HOLE-TRANSPORTING INK COMPOSITION, LIGHT-EMITTING DEVICE, AND METHOD OF PREPARING THE LIGHT-EMITTING DEVICE | Samsung Display Co., Ltd. (KR) | 2021-12-01 | — | — | EP | disclosed |