Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447093 | 1.00 | CYP1A2 (0.53) | CYP1A2TAAR1PLK4PAK4NTRK1 | |
| SCHEMBL1447134 | 0.92 | CYP1A2 (0.53) | CYP1A2TAAR1PLK4PAK4NTRK1 | |
| SCHEMBL1447116 | 0.89 | CYP1A2 (0.48) | CYP1A2TAAR1PLK4PAK4NTRK1 | |
| SCHEMBL1446006 | 0.89 | CYP1A2 (0.48) | CYP1A2TAAR1PLK4PAK4NTRK1 | |
| SCHEMBL1446217 | 0.89 | CYP1A2 (0.40) | CYP1A2PLK4MAPTKDM4EMEN1 | |
| SCHEMBL1447195 | 0.89 | CYP1A2 (0.40) | CYP1A2PLK4MAPTKDM4EMEN1 | |
| SCHEMBL1446421 | 0.84 | TAAR1 (0.54) | CYP1A2TAAR1NPC1RAB9AMAPT | |
| SCHEMBL1446014 | 0.84 | CYP1A2 (0.54) | CYP1A2TAAR1PLK4PAK4NTRK1 | |
| SCHEMBL1446374 | 0.83 | CYP1A2 (0.53) | CYP1A2TAAR1PLK4PAK4NTRK1 | |
| SCHEMBL1446376 | 0.82 | CYP1A2 (0.51) | CYP1A2TAAR1PLK4PAK4NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324511-A1 | Compounds, Compositions and Methods | CYTOKINETICS, INC. | 2009-12-31 | — | — | US | claimed |
| US-7910743-B2 | Compounds, compositions and methods | CYTOKINETICS, INC. (US) | 2011-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324511-A1 | Compounds, Compositions and Methods | TNNI3, TNNC1, TNNT2 | CYP1A2 4662/4885TAAR1 4657/4885PLK4 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.