Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.30 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14461265 | 0.87 | ALDH1A1 (0.32) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22661865 | 0.87 | — | — | |
| SCHEMBL13886632 | 0.83 | ALDH1A1 (0.43) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL195669 | 0.83 | ALDH1A1 (0.43) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL36956 | 0.82 | L3MBTL1 (0.42) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4650027 | 0.82 | L3MBTL1 (0.42) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13615687 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14099683 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12337529 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12928332 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130006118-A1 | RADIATIVE FIBERS | MERCK PATENT GMBH (DE) | 2013-01-03 | — | — | US | disclosed |