Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810682 | 0.78 | GSK3B (0.41) | GSK3BGPR35POLBTDP1L3MBTL1 | |
| SCHEMBL3045573 | 0.77 | GPR35 (0.44) | GSK3BGPR35POLBTDP1L3MBTL1 | |
| SCHEMBL19119540 | 0.71 | GSK3B (0.36) | GSK3B | |
| SCHEMBL27470744 | 0.69 | TDP1 (0.38) | GSK3BGPR35TDP1L3MBTL1 | |
| SCHEMBL11597162 | 0.69 | GAA (0.35) | GSK3BGPR35 | |
| SCHEMBL2722085 | 0.68 | F10 (0.41) | GSK3BGPR35POLBTDP1L3MBTL1 | |
| SCHEMBL19335605 | 0.64 | — | — | |
| SCHEMBL8306941 | 0.64 | F10 (0.41) | GSK3BGPR35POLB | |
| SCHEMBL10186088 | 0.63 | GPR35 (0.66) | GPR35 | |
| SCHEMBL27447830 | 0.62 | GSK3B (0.61) | GSK3BGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123291-B1 | PROCESS FOR PREPARING 3-(SUBSTITUTED PHENYL)-5-THIENYL OR FURYL)-1,2,4-TRIAZOLES AND NOVEL INTERMEDIATES UTILIZED THEREIN | DOW AGROSCIENCES LLC (US) | 2007-07-18 | — | — | EP | disclosed |