Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 11/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12261076 | 0.80 | GPR35 (0.46) | GPR35GSK3BPOLBTDP1L3MBTL1 | |
| SCHEMBL321098 | 0.80 | GPR35 (0.60) | GPR35GSK3BPOLBTDP1L3MBTL1 | |
| SCHEMBL7810682 | 0.80 | GSK3B (0.41) | GPR35GSK3BPOLBTDP1L3MBTL1 | |
| SCHEMBL1629386 | 0.78 | GPR35 (0.44) | GPR35GSK3B | |
| SCHEMBL27447830 | 0.77 | GSK3B (0.61) | GPR35GSK3BCES2CES1 | |
| SCHEMBL14463157 | 0.77 | GSK3B (0.39) | GPR35GSK3BPOLBTDP1L3MBTL1 | |
| SCHEMBL16046036 | 0.76 | GSK3B (0.44) | GPR35GSK3BPOLBCES2CES1 | |
| SCHEMBL1529989 | 0.75 | MAPT (0.46) | GPR35POLBTDP1KMT2A | |
| SCHEMBL12261073 | 0.75 | GPR35 (0.42) | GPR35GSK3BPOLB | |
| SCHEMBL8306941 | 0.74 | F10 (0.41) | GPR35GSK3BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150184307-A1 | SILVER ELECTROPLATING SOLUTION | DAIWA FINE CHEMICALS CO., LTD. (LABORATORY) (JP) | 2015-07-02 | — | — | US | disclosed |
| EP-2881497-A1 | ELECTROSILVER PLATING FLUID | Daiwa Fine Chemicals Co., Ltd. (JP) | 2015-06-10 | — | — | EP | disclosed |
| US-8541406-B2 | Thiadiazole derivatives for the treatment of neurodegenerative diseases | NV REMYND (BE) | 2013-09-24 | — | — | US | disclosed |
| US-20100261707-A9 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | NV REMYND (BE) | 2010-10-14 | — | — | US | disclosed |
| US-20090233911-A2 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | NV REMYND (BE) | 2009-09-17 | — | — | US | disclosed |
| US-20090054410-A1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | NV REMYND (BE) | 2009-02-26 | — | — | US | disclosed |
| US-20070284258-A1 | Method For Silver Plating | DAIWA FINE CHEMICALS CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |
| EP-1123291-B1 | PROCESS FOR PREPARING 3-(SUBSTITUTED PHENYL)-5-THIENYL OR FURYL)-1,2,4-TRIAZOLES AND NOVEL INTERMEDIATES UTILIZED THEREIN | DOW AGROSCIENCES LLC (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1123291-B1 | PROCESS FOR PREPARING 3-(SUBSTITUTED PHENYL)-5-THIENYL OR FURYL)-1,2,4-TRIAZOLES AND NOVEL INTERMEDIATES UTILIZED THEREIN | DOW AGROSCIENCES LLC (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1123290-B1 | 3-(SUBSTITUTED PHENYL)-5-THIENYL-1,2,4-TRIAZOLE COMPOUNDS WITH ACTIVITY AGAINST WHITEFLY | DOW AGROSCIENCES LLC (US) | 2003-02-19 | — | — | EP | disclosed |
| US-6329528-B1 | REACTING ALKYL BENZTHIOIMIDATE OR ITS ACID ADDITION SALT WITH FURAN OR THIOFURAN ACID CHLORIDE COMPOUND TO PRODUCT ADDUCT-INTERMEDIATE; REACTING WITH METHYLHYDRAZINE TO PRODUCE 3-(SUBSTITUTED PHENYL)-5-THIENYL OR FURYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC | 2001-12-11 | — | — | US | disclosed |
| EP-1123291-A1 | PROCESS FOR PREPARING 3-(SUBSTITUTED PHENYL)-5-THIENYL OR FURYL)-1,2,4-TRIAZOLES AND NOVEL INTERMEDIATES UTILIZED THEREIN | Dow Agrosciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-1123290-A1 | 3-(SUBSTITUTED PHENYL)-5-THIENYL-1,2,4-TRIAZOLE COMPOUNDS WITH ACTIVITY AGAINST WHITEFLY | Dow AgroSciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| US-6265424-B1 | INSECTICIDES, MITICIDES | DOW AGROSCIENCES LLC | 2001-07-24 | — | — | US | disclosed |
| WO-2000024738-A1 | PROCESS FOR PREPARING 3-(SUBSTITUTED PHENYL)-5-THIENYL OR FURYL)-1,2,4-TRIAZOLES AND NOVEL INTERMEDIATES UTILIZED THEREIN | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
| WO-2000024737-A1 | 3-(SUBSTITUTED PHENYL)-5-THIENYL-1,2,4-TRIAZOLE COMPOUNDS WITH ACTIVITY AGAINST WHITEFLY | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233911-A2 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PARK7 | GPR35 923/4885GSK3B 175/4885POLB 3933/4885 |
| US-20100261707-A9 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PARK7 | GPR35 923/4885GSK3B 175/4885POLB 3933/4885 |
| US-20090054410-A1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PARK7 | GPR35 923/4885GSK3B 175/4885POLB 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.