Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.67 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.67 |
| ▸ | MRGPRX2 | Q96LB1 | 5/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.67 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13668804 | 1.00 | OPRM1 (0.67) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL13656808 | 1.00 | OPRM1 (0.67) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL18867882 | 1.00 | OPRM1 (0.67) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL14154485 | 0.91 | OPRM1 (0.55) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL13151540 | 0.86 | OPRM1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL19880922 | 0.86 | OPRM1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL18867761 | 0.86 | OPRM1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL12283963 | 0.86 | OPRM1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL14501896 | 0.86 | OPRM1 (0.55) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL22971571 | 0.83 | OPRM1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1810973-A1 | 6-monoacetylmorphine derivatives useful in immunoassay | Roche Diagnostics GmbH (DE) | 2007-07-25 | — | — | EP | disclosed |