Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.66 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.66 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12283963 | 1.00 | OPRM1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL18867761 | 1.00 | OPRM1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL19880922 | 1.00 | OPRM1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL13668804 | 0.86 | OPRM1 (0.67) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL14501898 | 0.86 | OPRD1 (0.49) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL14463456 | 0.86 | OPRM1 (0.67) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL18867882 | 0.86 | OPRM1 (0.67) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL13656808 | 0.86 | OPRM1 (0.67) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL14501897 | 0.84 | OPRM1 (0.55) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL22536510 | 0.83 | OPRD1 (0.61) | OPRM1OPRD1OPRK1MRGPRX2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| WO-2010121369-A1 | PROCESSES FOR THE PREPARATION OF MORPHINANE AND MORPHINONE COMPOUNDS | BROCK UNIVERSITY (CA) | 2010-10-28 | — | — | WO | disclosed |