Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18040333 | 0.88 | KIF11 (0.45) | KIF11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13553389 | 0.88 | KIF11 (0.37) | KIF11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL14508116 | 0.84 | MAPT (0.31) | KIF11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL14435170 | 0.82 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL25475487 | 0.81 | KIF11 (0.39) | KIF11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL27697517 | 0.79 | KIF11 (0.38) | KIF11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13892802 | 0.74 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL27697520 | 0.74 | KDM4E (0.37) | SMN1; SMN2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL14049040 | 0.73 | CNR2 (0.32) | — | |
| SCHEMBL14515083 | 0.73 | NPC1 (0.38) | KIF11NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074325-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | CDT OXFORD LIMITED (GB) | 2007-07-05 | — | — | WO | disclosed |