Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435170 | 0.90 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL13553389 | 0.85 | KIF11 (0.37) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL12348738 | 0.80 | RAB9A (0.34) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL3630819 | 0.78 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL13846358 | 0.76 | — | — | |
| SCHEMBL22245948 | 0.76 | RAB9A (0.36) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16450316 | 0.75 | CNR1 (0.32) | CNR1CNR2 | |
| SCHEMBL15165408 | 0.75 | CNR1 (0.32) | CNR1CNR2 | |
| SCHEMBL14493024 | 0.74 | CNR2 (0.33) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL14463577 | 0.74 | KIF11 (0.37) | NPC1RAB9ASMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048176-A1 | POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |