Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 2/20 | 0.71 |
| ▸ | NAT1 | P18440 | 5/20 | 0.66 |
| ▸ | GSK3B | P49841 | 2/20 | 0.62 |
| ▸ | MYC | P01106 | 1/20 | 0.60 |
| ▸ | MAX | P61244 | 1/20 | 0.60 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174037 | 1.00 | PTP4A3 (0.71) | PTP4A3NAT1GSK3BMYCMAX | |
| SCHEMBL18102943 | 0.86 | PTP4A3 (0.75) | PTP4A3NAT1GSK3BMYCMAX | |
| SCHEMBL3405860 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1GSK3BMYCMAX | |
| SCHEMBL18102858 | 0.83 | PTP4A3 (0.75) | PTP4A3NAT1GSK3BMYCMAX | |
| SCHEMBL13616173 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1GSK3BMYCMAX | |
| SCHEMBL14464055 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1GSK3BMYCMAX | |
| SCHEMBL3405858 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1GSK3BMYCMAX | |
| SCHEMBL14464056 | 0.83 | PTP4A3 (1.00) | PTP4A3NAT1GSK3BMYCMAX | |
| SCHEMBL14226382 | 0.83 | NAT1 (0.69) | PTP4A3NAT1GSK3BMEN1POLB | |
| SCHEMBL19659989 | 0.83 | CA2 (0.71) | PTP4A3NAT1GSK3BMYCMAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |