Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 6/20 | 0.76 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921368 | 0.93 | ALDH1A1 (0.75) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL854050 | 0.92 | ALDH1A1 (0.71) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL13455233 | 0.92 | ALDH1A1 (0.69) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL30198175 | 0.92 | ALDH1A1 (0.71) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL1127011 | 0.92 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL30928952 | 0.92 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL85672 | 0.92 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL31342236 | 0.91 | ALDH1A1 (0.68) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL5058298 | 0.90 | ALDH1A1 (0.71) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL7814507 | 0.90 | ALDH1A1 (0.66) | ALDH1A1KMT2ALMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703939-B2 | Method for preparing (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives | LEGOCHEM BIOSCIENCES, INC. (KR) | 2014-04-22 | — | — | US | disclosed |
| US-8703939-B2 | Method for preparing (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives | LEGOCHEM BIOSCIENCES, INC. (KR) | 2014-04-22 | — | — | US | disclosed |
| US-20130005967-A1 | METHOD FOR PREPARING (R)-3-(3-FLUORO-4-(1-METHYL-5,6-DIHYDRO-1,2,4-TRIAZIN-4(1H)-YL)PHENYL)-5-(SUBSTITUTED METHYL)OXAZOLIDIN-2-ONE DERIVATIVES | LEGOCHEM BIOSCIENCES, INC. (KR) | 2013-01-03 | — | — | US | disclosed |
| US-20130005967-A1 | METHOD FOR PREPARING (R)-3-(3-FLUORO-4-(1-METHYL-5,6-DIHYDRO-1,2,4-TRIAZIN-4(1H)-YL)PHENYL)-5-(SUBSTITUTED METHYL)OXAZOLIDIN-2-ONE DERIVATIVES | LEGOCHEM BIOSCIENCES, INC. (KR) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005967-A1 | METHOD FOR PREPARING (R)-3-(3-FLUORO-4-(1-METHYL-5,6-DIHYDRO-1,2,4-TRIAZIN-4(1H)-YL)PHENYL)-5-(SUBSTITUTED METHYL)OXAZOLIDIN-2-ONE DERIVATIVES | TET1, AZI2, OXA1L | ALDH1A1 1220/4885KMT2A 413/4885LMNA 3338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.