SCHEMBL30928952

SCHEMBL30928952

O=[N+]([O-])c1ccc(N2CCCCC2)c(F)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.73
KMT2A Q03164 2/20 0.73
GAA P10253 1/20 0.69
LMNA P02545 3/20 0.66
SMN1; SMN2 Q16637 4/20 0.62
CYP1A2 P05177 2/20 0.59
CYP3A4 P08684 2/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2C19 P33261 2/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HPGD P15428 1/20 0.59
MEN1 O00255 1/20 0.59
SLC6A9 P48067 1/20 0.59
SLC6A5 Q9Y345 1/20 0.59
MAPT P10636 5/20 0.59
THRB P10828 1/20 0.59
HTT P42858 2/20 0.57
MITF O75030 1/20 0.57
HSP90AA1 P07900 1/20 0.57
CYP2D6 P10635 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85672 1.00 ALDH1A1 (0.73) ALDH1A1KMT2AGAALMNASMN1; SMN2
SCHEMBL1127011 1.00 ALDH1A1 (0.73) ALDH1A1KMT2AGAALMNASMN1; SMN2
SCHEMBL4921368 0.98 ALDH1A1 (0.75) ALDH1A1KMT2AGAALMNASMN1; SMN2
SCHEMBL5697459 0.95 ALDH1A1 (0.68) ALDH1A1KMT2AGAALMNASMN1; SMN2
SCHEMBL6687570 0.93 MAPT (0.69) ALDH1A1KMT2AGAALMNASMN1; SMN2
SCHEMBL14464189 0.92 ALDH1A1 (0.79) ALDH1A1KMT2AGAALMNASMN1; SMN2
SCHEMBL18396735 0.88 ALDH1A1 (0.66) ALDH1A1KMT2AGAALMNASMN1; SMN2
SCHEMBL30843930 0.87 GAA (0.65) ALDH1A1KMT2AGAALMNASMN1; SMN2
SCHEMBL1640562 0.86 ALDH1A1 (0.60) ALDH1A1KMT2AGAALMNASMN1; SMN2
SCHEMBL5058298 0.86 ALDH1A1 (0.71) ALDH1A1KMT2AGAALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4434980-A1 MULTIFUNCTIONAL COMPOUND CAPABLE OF DEGRADING BTK KINASE, AND COMPOSITION AND USE Hangzhou HealZen Therapeutics Co., Ltd. (CN) 2024-09-25 EP disclosed
CN-113880813-B 2-Aminopyrimidine heterocyclic compound and application thereof 杭州百诚医药科技股份有限公司 2024-05-28 CN disclosed