Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10075274 | 0.86 | SMN1; SMN2 (0.35) | MGLLALDH1A1KMT2AMEN1ATM | |
| SCHEMBL15502949 | 0.86 | MGLL (0.34) | MGLLKMT2AATM | |
| SCHEMBL13682852 | 0.85 | PSMB8 (0.33) | MGLLALDH1A1KMT2AATM | |
| SCHEMBL7006081 | 0.85 | ACE (0.34) | MGLLKMT2AATM | |
| SCHEMBL22758156 | 0.84 | ALDH1A1 (0.36) | MGLLALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL18219194 | 0.84 | ALDH1A1 (0.36) | MGLLALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL29308002 | 0.84 | ALDH1A1 (0.36) | MGLLALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL327627 | 0.83 | HPGD (0.34) | MGLLALDH1A1HTTKMT2AATM | |
| SCHEMBL10026333 | 0.83 | CA1 (0.37) | MGLLALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2607894 | 0.83 | MGLL (0.33) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2898900-A1 | Polymer conjugates of ziconotide | Nektar Therapeutics (US) | 2015-07-29 | — | — | EP | disclosed |
| WO-2007075534-A2 | POLYMER CONJUGATES OF GLP-1 | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |