Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13600067 | 0.77 | POLB (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL208307 | 0.71 | ALDH1A1 (0.51) | ALDH1A1KMT2AHRH3CYP2D6 | |
| SCHEMBL19562096 | 0.66 | MAOB (0.58) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL14452939 | 0.66 | EPHX2 (0.60) | ALDH1A1KMT2AMEN1HRH3CYP2D6 | |
| Hydrochloric Acid SCHEMBL1597604 | 0.66 | TSHR (0.64) | ALDH1A1SMN1; SMN2LMNACYP3A4CYP2C9 | |
| SCHEMBL209672 | 0.65 | GPR119 (0.49) | ALDH1A1HRH3CYP3A4POLB | |
| SCHEMBL10495198 | 0.65 | ALDH1A1 (0.89) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL23709723 | 0.65 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL31350856 | 0.64 | MAOB (0.82) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP2D6 | |
| SCHEMBL9426221 | 0.64 | CHRNA7 (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075629-A2 | PHENOXYPIPERIDINES AND ANALOGS THEREOF USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |