SCHEMBL14465504

SCHEMBL14465504

CN(c1ccc(-c2ccccc2)cc1)c1ccc2c(c1)C1(c3ccccc3-c3ccccc31)c1cc(N(c3ccccc3)c3ccccc3)ccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 10/20 0.53
CHKA P35790 2/20 0.34
NR3C2 P08235 1/20 0.33
GSK3B P49841 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PDE5A O76074 2/20 0.31
MAPT P10636 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.30
APAF1 O14727 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14465465 0.97 PDK2 (0.56) PDK2CHKANR3C2MAPTL3MBTL1
SCHEMBL279228 0.94 PDK2 (0.58) PDK2CHKANR3C2HSP90AA1MAPT
SCHEMBL14465498 0.93 PDK2 (0.49) PDK2CHKANR3C2MAPTL3MBTL1
SCHEMBL14466292 0.93 PDK2 (0.56) PDK2CHKANR3C2HSP90AA1MAPT
SCHEMBL279367 0.93 PDK2 (0.56) PDK2CHKANR3C2HSP90AA1MAPT
SCHEMBL279070 0.93 PDK2 (0.59) PDK2CHKANR3C2HSP90AA1MAPT
SCHEMBL14466528 0.93 PDK2 (0.56) PDK2NR3C2HSP90AA1MAPTL3MBTL1
SCHEMBL18627671 0.93 PDK2 (0.56) PDK2CHKANR3C2MAPTL3MBTL1
SCHEMBL21922872 0.92 PDK2 (0.42) PDK2MAPTL3MBTL1KDM4EALDH1A1
SCHEMBL21922943 0.92 PDK2 (0.42) PDK2MAPTL3MBTL1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9048436-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-02 US disclosed
US-9048436-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-02 US disclosed
EP-1976838-B1 OXADIAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE OXADIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2015-02-25 EP disclosed
US-20140299822-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-09 US disclosed
US-20140299822-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-09 US disclosed
US-20130200344-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-08-08 US disclosed
US-20130200344-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-08-08 US disclosed
US-8389735-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-05 US disclosed
US-8389735-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-05 US disclosed
WO-2007074893-A1 OXADIAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE OXADIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-07-05 WO disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative OXA1L, ADRA1D, CRY1 PDK2 713/4885CHKA 4135/4885NR3C2 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.