Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242815 | 0.92 | APP (0.42) | APPTDP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL14466729 | 0.91 | APP (0.36) | APPTDP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL13304647 | 0.90 | MAOB (0.47) | APPKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL14466717 | 0.86 | KDM4E (0.34) | APPKDM4EALDH1A1INSR | |
| SCHEMBL20109433 | 0.84 | APP (0.45) | APPTDP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL10110902 | 0.83 | ALDH1A1 (0.44) | TDP1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13242716 | 0.82 | APP (0.56) | APPTDP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL14466727 | 0.82 | APP (0.46) | APPTDP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL12888139 | 0.81 | ALDH1A1 (0.42) | TDP1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12777543 | 0.81 | ALDH1A1 (0.33) | APPTDP1KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075268-A1 | ELECTROLUMINESCENT DEVICE CONTAINING A BUTADIENE DERIVATIVE | EASTMAN KODAK COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20070141388-A1 | Electroluminescent device containing a butadiene derivative | EASTMAN KODAK COMPANY | 2007-06-21 | — | — | US | disclosed |
| US-20070141388-A1 | Electroluminescent device containing a butadiene derivative | EASTMAN KODAK COMPANY | 2007-06-21 | — | — | US | disclosed |