SCHEMBL20109433

SCHEMBL20109433

Cc1ccc(N(c2ccccc2)c2ccc(/C=C/C=C/c3ccc(N(c4ccccc4)c4ccc(C)cc4)c4ccccc34)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.45
TRPM8 Q7Z2W7 2/20 0.40
KDM4E B2RXH2 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
RELA Q04206 1/20 0.35
NFE2L2 Q16236 1/20 0.35
MAOB P27338 1/20 0.34
ALDH1A1 P00352 5/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 2/20 0.33
MAPK1 P28482 2/20 0.33
KMT2A Q03164 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13237078 0.90 APP (0.40) APPTRPM8KDM4ERAB9ACASP3
SCHEMBL18157326 0.90 NPC1 (0.36) APPTRPM8KDM4ENPC1RAB9A
SCHEMBL18157328 0.88 PTGS2 (0.41) APPTRPM8NPC1RAB9ANFE2L2
SCHEMBL13237082 0.88 APP (0.42) APPTRPM8KDM4ERAB9ACASP3
SCHEMBL13807862 0.88 APP (0.50) APPTRPM8KDM4ENPC1RAB9A
SCHEMBL14537276 0.87 TRPM8 (0.46) APPTRPM8KDM4ENPC1RAB9A
SCHEMBL14466727 0.86 APP (0.46) APPKDM4ENPC1RAB9ARELA
SCHEMBL14099255 0.85 APP (0.43) APPTRPM8KDM4ENPC1RAB9A
SCHEMBL11976748 0.85 ALDH1A1 (0.38) APPTRPM8KDM4ENPC1RAB9A
SCHEMBL13311202 0.85 APP (0.46) APPTRPM8KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10012916-B2 Photoreceptor for electrophotography, and photoreceptor cartridge and image forming apparatus employing the same S-PRINTING SOLUTION CO., LTD. (KR) 2018-07-03 US disclosed
US-10012916-B2 Photoreceptor for electrophotography, and photoreceptor cartridge and image forming apparatus employing the same S-PRINTING SOLUTION CO., LTD. (KR) 2018-07-03 US disclosed
US-20180120716-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, AND PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS EMPLOYING THE SAME S-PRINTING SOLUTION CO., LTD. (KR) 2018-05-03 US disclosed
US-20180120716-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, AND PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS EMPLOYING THE SAME S-PRINTING SOLUTION CO., LTD. (KR) 2018-05-03 US disclosed