Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316315 | 1.00 | ACACB (0.50) | ACACBELANEPPARAMEN1KMT2A | |
| SCHEMBL14650783 | 0.84 | EPHX2 (0.47) | ACACBKMT2AHPGDALDH1A1 | |
| SCHEMBL28163275 | 0.80 | ACACB (0.49) | ACACBELANEPPARAMEN1KMT2A | |
| SCHEMBL5316313 | 0.79 | CES2 (0.48) | ACACBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL5319395 | 0.79 | CES2 (0.48) | ACACBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL18287905 | 0.78 | ELANE (0.55) | ACACBELANEPPARAMEN1KMT2A | |
| SCHEMBL6055221 | 0.76 | ACACB (0.47) | ACACBELANEPPARAMEN1KMT2A | |
| SCHEMBL28776058 | 0.76 | ACACB (0.51) | ACACBELANEPPARAMEN1KMT2A | |
| SCHEMBL9276609 | 0.75 | TSHR (0.54) | MEN1KMT2AMAPTCYP1A2ALDH1A1 | |
| SCHEMBL24360844 | 0.74 | GABBR2 (0.44) | ACACBELANEPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077140-A1 | HYDROXY-NOREPHEDRINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |