Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14465959 | 0.83 | MET (0.44) | MET | |
| SCHEMBL14465811 | 0.82 | MET (0.43) | MET | |
| SCHEMBL2495186 | 0.80 | MET (0.46) | MET | |
| SCHEMBL2495195 | 0.73 | MET (0.60) | MET | |
| SCHEMBL2676115 | 0.73 | MET (0.53) | MET | |
| SCHEMBL2493598 | 0.73 | MET (0.50) | MET | |
| SCHEMBL2492886 | 0.72 | MET (0.61) | MET | |
| SCHEMBL4826052 | 0.71 | MET (0.48) | MET | |
| SCHEMBL2493583 | 0.71 | MET (0.59) | MET | |
| SCHEMBL2491763 | 0.71 | MET (0.47) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075567-A1 | TRIAZOLOPYRIDAZINES AS TYROSINE KINASE MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-07-05 | — | — | WO | disclosed |