Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763937 | 0.99 | TLR7 (0.52) | TLR7ALDH1A1NPSR1KDM4EHSD17B10 | |
| SCHEMBL4763092 | 0.90 | TLR7 (0.62) | TLR7TLR8NUDT1BRD4 | |
| SCHEMBL4762062 | 0.85 | TLR7 (0.49) | TLR7ALDH1A1KDM4EHSD17B10TLR8 | |
| SCHEMBL4792564 | 0.83 | TLR7 (0.52) | TLR7ALDH1A1NPSR1KDM4EHSD17B10 | |
| SCHEMBL18179115 | 0.83 | TLR7 (0.49) | TLR7ALDH1A1TLR8NUDT1LMNA | |
| SCHEMBL5160131 | 0.82 | TLR7 (0.54) | TLR7ALDH1A1NPSR1KDM4EHSD17B10 | |
| SCHEMBL4761822 | 0.82 | ALDH1A1 (0.46) | TLR7ALDH1A1NPSR1KDM4EHSD17B10 | |
| SCHEMBL5454507 | 0.82 | TLR7 (0.47) | TLR7TLR8NUDT1LMNABRD4 | |
| SCHEMBL4754407 | 0.80 | TLR7 (0.38) | TLR7KDM4ETLR8NUDT1L3MBTL1 | |
| SCHEMBL6099996 | 0.80 | TLR8 (0.49) | TLR7ALDH1A1KDM4ETLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075468-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-05 | — | — | WO | disclosed |