SCHEMBL1446598

SCHEMBL1446598

CC(=NO)C(C)(C)NCC(N)CNC(C)(C)C(C)=NO

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1446594 1.00 POLB (0.34) POLB
SCHEMBL15895095 0.81 POLB (0.35) POLB
SCHEMBL5485586 0.79
SCHEMBL6131615 0.79 POLB (0.32) POLB
SCHEMBL10156702 0.78 POLB (0.33) POLB
Hydrochloric Acid SCHEMBL6131561 0.77 POLB (0.31) POLB
SCHEMBL15494039 0.76 POLB (0.33) POLB
SCHEMBL10005608 0.75 POLB (0.39) POLB
SCHEMBL7128026 0.72 POLB (0.35) POLB
SCHEMBL5313285 0.72 POLB (0.30) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9629934-B2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy DYAX CORP. (US) 2017-04-25 US disclosed
US-9446155-B2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy BRACCO SUISSE SA (CH) 2016-09-20 US disclosed
US-9408926-B2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy BRACCO SUISSE S.A. (CH) 2016-08-09 US disclosed
US-20140286864-A1 KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY BRACCO SUISSE SA (CH) 2014-09-25 US disclosed
EP-2301587-B1 KDR and VEGF/KDR binding peptides and their use in diagnosis DYAX CORP (US) 2014-06-25 EP disclosed
US-20140161732-A1 KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY BRACCO SUISSE S.A. (CH) 2014-06-12 US disclosed
US-20140107041-A1 KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY DYAX CORP. (US) 2014-04-17 US disclosed
US-8642010-B2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy DYAX CORP. (US) 2014-02-04 US disclosed
US-8623822-B2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy BRACCO SUISSE SA (CH) 2014-01-07 US disclosed
EP-2014310-B1 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy DYAX CORP (US) 2012-10-24 EP disclosed
US-20110097275-A1 KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY BRACCO SUISSE SA (CH) 2011-04-28 US disclosed
EP-2301587-A2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy Dyax Corporation (US) 2011-03-30 EP disclosed
US-20100003195-A1 KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-01-07 US disclosed
EP-2014310-A2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy Dyax Corporation (US) 2009-01-14 EP disclosed
US-20050250700-A1 KDR and VEGF/KDR binding peptides BRACCO INTERNATIONAL B.V. (NL) 2005-11-10 US disclosed
US-20050100963-A1 Multimeric protein comprising endothelial growth factor (VEGF) and kinase domain region (KDR) for use in detection, prevention and treatment of cell proliferative, virral and infectious disorders DYAX CORPORATION (US) 2005-05-12 US disclosed