Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362130 | 0.88 | POLB (0.33) | POLBTSHR | |
| SCHEMBL8362134 | 0.88 | POLB (0.33) | POLBTSHR | |
| SCHEMBL8476513 | 0.86 | PAOX (0.38) | POLBTSHRSMN1; SMN2 | |
| SCHEMBL8476517 | 0.86 | PAOX (0.38) | POLBTSHRSMN1; SMN2 | |
| SCHEMBL8476697 | 0.84 | PAOX (0.41) | POLBTSHRSMN1; SMN2 | |
| SCHEMBL8476699 | 0.84 | PAOX (0.41) | POLBTSHRSMN1; SMN2 | |
| SCHEMBL8693325 | 0.82 | POLB (0.37) | POLBTSHRSMN1; SMN2 | |
| SCHEMBL8693335 | 0.82 | POLB (0.37) | POLBTSHRSMN1; SMN2 | |
| Upenazime SCHEMBL1477985 | 0.82 | POLB (0.37) | POLBTSHRSMN1; SMN2 | |
| SCHEMBL12082868 | 0.81 | POLB (0.30) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660246-B1 | 3,3,9,9-Tetramethyl-4,8-diazaundecane-2,10-dione 2-Hydrazone 10-Oxime; | BRACCO INTERNATIONAL, BV (NL) | 2003-12-09 | — | — | US | disclosed |
| EP-0688313-B1 | LIGANDS AND METAL COMPLEXES THEREOF | BRACCO INT BV (NL) | 1998-04-08 | — | — | EP | disclosed |
| US-5663307-A | Hydrazone containing ligands and metal complexes thereof | BRACCO INTERNATIONAL B.V. | 1997-09-02 | — | — | US | disclosed |
| US-5651954-A | Method of using hydrazone containing ligands and metal complexes thereof | BRACCO INTERNATIONAL B.V. (NL) | 1997-07-29 | — | — | US | disclosed |