⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446594 | 0.79 | POLB (0.34) | — | |
| SCHEMBL1446598 | 0.79 | POLB (0.34) | — | |
| SCHEMBL15895095 | 0.67 | POLB (0.35) | — | |
| SCHEMBL6131615 | 0.65 | POLB (0.32) | — | |
| SCHEMBL10156702 | 0.64 | POLB (0.33) | — | |
| Hydrochloric Acid SCHEMBL6131561 | 0.64 | POLB (0.31) | — | |
| SCHEMBL15494039 | 0.63 | POLB (0.33) | — | |
| SCHEMBL10005608 | 0.62 | POLB (0.39) | — | |
| SCHEMBL7128026 | 0.60 | POLB (0.35) | — | |
| SCHEMBL5313285 | 0.60 | POLB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587944-A4 | KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY | DYAX CORP (US) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006031885-A2 | KDR AND VEGF/KDR BINDING PEPTIDES | DYAX CORP. (US) | 2006-03-23 | — | — | WO | disclosed |
| EP-1587944-A1 | KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY | Dyax Corp. (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004065621-A1 | KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY | DYAX CORP. (US) | 2004-08-05 | — | — | WO | disclosed |