Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 16/20 | 0.71 |
| ▸ | MTTP | P55157 | 15/20 | 0.71 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10265197 | 0.83 | APOB (1.00) | APOBMTTPSMO | |
| SCHEMBL13591653 | 0.77 | APOB (0.88) | APOBMTTPSMO | |
| SCHEMBL10406586 | 0.77 | TBXA2R (0.65) | APOBMTTPTBXA2RNR1H2 | |
| SCHEMBL4783524 | 0.71 | TBXA2R (0.54) | APOBMTTPTBXA2RNR1H2 | |
| SCHEMBL4781106 | 0.71 | APOB (0.47) | APOBMTTPNR1H2 | |
| SCHEMBL13591642 | 0.70 | APOB (0.87) | APOBMTTPSMO | |
| SCHEMBL10405638 | 0.70 | TBXA2R (0.65) | APOBMTTPTBXA2RNR1H2 | |
| SCHEMBL13591630 | 0.70 | APOB (0.79) | APOBMTTPSMO | |
| SCHEMBL4784895 | 0.70 | APOB (0.46) | APOBMTTPNR1H2 | |
| SCHEMBL10406410 | 0.69 | TBXA2R (0.55) | APOBMTTPTBXA2RNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803452-A1 | ESTER DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2007-07-04 | — | — | EP | disclosed |