Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12949972 | 1.00 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL13152662 | 0.95 | RAB9A (0.39) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL10097435 | 0.93 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL12489610 | 0.93 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL12487872 | 0.92 | PDE7A (0.34) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL14467126 | 0.92 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL10097623 | 0.92 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL13214767 | 0.90 | DYRK1A (0.38) | SMN1; SMN2RAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL13052762 | 0.90 | HPGD (0.38) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL10097501 | 0.90 | ALDH1A1 (0.47) | MEN1KMT2ARAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084435-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |