Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 3/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14467197 | 1.00 | PIK3CA (0.37) | PIK3CAPIK3C3HTR1AHTR2AHTR7 | |
| SCHEMBL14354273 | 0.92 | AGTR1 (0.40) | PIK3CAPIK3C3HTR6AKT1MTOR | |
| SCHEMBL12333286 | 0.92 | AGTR1 (0.40) | PIK3CAPIK3C3HTR6AKT1MTOR | |
| SCHEMBL12333391 | 0.76 | CYP11B1 (0.33) | PIK3CAPIK3C3AKT1AGTR1CYP11B1 | |
| SCHEMBL12333120 | 0.75 | HTT (0.40) | PIK3CAPIK3C3HTR6AKT1MTOR | |
| SCHEMBL29277557 | 0.70 | AGTR1 (0.49) | PIK3CAHTR1AHTR2AHTR7HTR6 | |
| SCHEMBL12333390 | 0.69 | PIK3CD (0.44) | PIK3CAHTR6AKT1MTORAGTR1 | |
| SCHEMBL27892301 | 0.68 | KMO (0.49) | HTR1AHTR2AHTR7HTR6AURKA | |
| SCHEMBL21870386 | 0.67 | ESR1 (0.41) | NPC1RAB9AIDO1TDO2 | |
| SCHEMBL22549302 | 0.65 | ESR1 (0.51) | NPC1RAB9AIDO1TDO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130005979-A1 | THIENOPYRIDINE DERIVATIVE, METHOD FOR PRODUCING SAME AND ORGANIC SEMICONDUCTOR DEVICE USING SAME | KURARAY CO. LTD. (JP) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005979-A1 | THIENOPYRIDINE DERIVATIVE, METHOD FOR PRODUCING SAME AND ORGANIC SEMICONDUCTOR DEVICE USING SAME | TPMT, TET1, TYMS | PIK3CA 1148/4885PIK3C3 1358/4885HTR1A 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.