SCHEMBL1446748

SCHEMBL1446748

CCOC(C)(OCc1ccccc1)OC(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
KMT2A Q03164 2/20 0.50
SLC6A3 Q01959 2/20 0.50
SLC6A2 P23975 1/20 0.50
CYP2D6 P10635 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 2/20 0.41
GAA P10253 1/20 0.41
HTR1A P08908 1/20 0.40
SCN1A P35498 1/20 0.40
SCN5A Q14524 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27734197 0.91 CYP2D6 (0.54) TDP1KMT2ASLC6A3SLC6A2CYP2D6
SCHEMBL28161590 0.83 CYP2D6 (0.50) TDP1KMT2ASLC6A3SLC6A2CYP2D6
SCHEMBL11626056 0.81 TSHR (0.44) TDP1KMT2ASLC6A2CYP2D6LMNA
SCHEMBL27562525 0.80 ALDH1A1 (0.41) KMT2AL3MBTL1ALDH1A1MAPTSYK
SCHEMBL28688043 0.78 CYP2D6 (0.54) TDP1KMT2ASLC6A3SLC6A2CYP2D6
SCHEMBL22833248 0.76 CYP2D6 (0.47) TDP1KMT2ASLC6A3CYP2D6CYP1A2
SCHEMBL5962148 0.76 TSHR (0.55) TDP1LMNAL3MBTL1ALDH1A1TSHR
SCHEMBL784759 0.76 CYP2D6 (0.51) TDP1KMT2ASLC6A3SLC6A2CYP2D6
Ethylbenzene SCHEMBL16673245 0.74 SLC7A5 (0.55) TDP1KMT2ASLC6A3SLC6A2CYP2D6
SCHEMBL6027111 0.74 L3MBTL1 (0.56) TDP1KMT2ASLC6A3SLC6A2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8754019-B2 Pressure transmission medium and hydraulic device IDEMITSU KOSAN CO., LTD. (JP) 2014-06-17 US disclosed
US-20110105373-A1 PRESSURE TRANSMISSION MEDIUM AND HYDRAULIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-05-05 US disclosed
EP-2302022-A1 PRESSURE TRANSMISSION MEDIUM AND HYDRAULIC DEVICE Idemitsu Kosan Co., Ltd. (JP) 2011-03-30 EP disclosed