Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 2/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13153361 | 0.91 | TDP1 (0.40) | PRKACARPS6KB1GSK3BROCK1PIK3CA | |
| SCHEMBL13051524 | 0.88 | HRH3 (0.38) | NFE2L2RAD51PRKACARPS6KB1GSK3B | |
| SCHEMBL10097663 | 0.86 | TDP1 (0.42) | PIK3CALMNAMEN1TERTABCB11 | |
| SCHEMBL13051669 | 0.85 | NCF1 (0.35) | NCF1PIK3CALMNAPRKDCALDH1A1 | |
| SCHEMBL10097541 | 0.84 | MEN1 (0.37) | PRKACARPS6KB1ROCK1LMNAMEN1 | |
| SCHEMBL12487867 | 0.84 | HRH3 (0.46) | — | |
| SCHEMBL14466152 | 0.84 | PRKACA (0.41) | RAD51PRKACARPS6KB1GSK3BROCK1 | |
| SCHEMBL14466373 | 0.82 | MEN1 (0.41) | PRKACARPS6KB1GSK3BROCK1PIK3CA | |
| SCHEMBL14466335 | 0.81 | HTT (0.42) | LMNAMEN1THRBKMT2ATSHR | |
| SCHEMBL13052772 | 0.80 | EPHX2 (0.40) | PIK3CAMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |