Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 2/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12996115 | 0.87 | SMN1; SMN2 (0.34) | NCF1PRKDCALDH1A1SMN1; SMN2 | |
| SCHEMBL14467697 | 0.85 | ATM (0.33) | NCF1PRKDCPIK3CAALDH1A1LMNA | |
| SCHEMBL10097537 | 0.85 | PIK3CA (0.36) | PRKDCHTR3APIK3CAALDH1A1 | |
| SCHEMBL13052772 | 0.84 | EPHX2 (0.40) | EPHX2PIK3CAALDH1A1HPGD | |
| SCHEMBL13052768 | 0.83 | SMN1; SMN2 (0.36) | EPHX2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13199078 | 0.83 | EGFR (0.33) | FGFR4HTR3AALDH1A1LMNAHPGD | |
| SCHEMBL13052780 | 0.82 | EPHX2 (0.35) | EPHX2HTR3AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10097529 | 0.82 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL13051939 | 0.82 | ALDH1A1 (0.34) | EPHX2HTR3AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10097541 | 0.81 | MEN1 (0.37) | ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305100-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305100-A1 | METHODS FOR TREATING HEPATITIS C | HAVCR2, EIF2AK2, MAVS | NCF1 917/4885PRKDC 2987/4885PPARG 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.