Valeric Acid

Valeric Acid

SCHEMBL144677

CCCCC(=O)[O-].CC[N+](C)(CC)CCOC

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 7/20 0.62
CA1 P00915 1/20 0.52
FABP3 P05413 5/20 0.39
FFAR3 O14843 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexanoate SCHEMBL2762333 0.95 BBOX1 (0.61) BBOX1CA1FABP3CES2CES1
Dodecanoate SCHEMBL2762624 0.94 BBOX1 (0.59) BBOX1CA1FABP3CES2CES1
Decanoic Acid SCHEMBL2762392 0.94 BBOX1 (0.59) BBOX1CA1FABP3CES2CES1
Dodecanoate SCHEMBL2761981 0.94 BBOX1 (0.59) BBOX1CA1FABP3CES2CES1
Heptanoate SCHEMBL2762419 0.94 BBOX1 (0.59) BBOX1CA1FABP3CES2CES1
Octanoic Acid SCHEMBL2761935 0.94 BBOX1 (0.59) BBOX1CA1FABP3CES2CES1
Butyric Acid SCHEMBL141251 0.90 BBOX1 (0.56) BBOX1CA1FFAR3HDAC3HDAC1
Valeric Acid SCHEMBL145773 0.87 BBOX1 (0.62) BBOX1CA1FABP3FFAR3HDAC3
Valeric Acid SCHEMBL145879 0.86 CA1 (0.55) BBOX1CA1FABP3
Valeric Acid SCHEMBL144555 0.85 BBOX1 (0.61) BBOX1CA1FABP3FFAR3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120058057-A1 Anti-dandruff Agents MERCK PATENT GMBH (DE) 2012-03-08 US claimed
WO-2010136104-A2 ANTI-DANDRUFF AGENTS MERCK PATENT GMBH (DE) 2010-12-02 WO claimed
US-20120058057-A1 Anti-dandruff Agents MERCK PATENT GMBH (DE) 2012-03-08 US disclosed
WO-2010136104-A2 ANTI-DANDRUFF AGENTS MERCK PATENT GMBH (DE) 2010-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120058057-A1 Anti-dandruff Agents POLR1C, ETF1, PIK3C3 BBOX1 416/4885CA1 1037/4885FABP3 1675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.