Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | MERTK | Q12866 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.37 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256723 | 1.00 | CFD (0.43) | CFDAPPACHEMERTKBCHE | |
| SCHEMBL14256696 | 0.86 | LATS1 (0.41) | APPACHEMERTKBCHECTNNB1 | |
| SCHEMBL14412304 | 0.84 | SMN1; SMN2 (0.35) | CFDAPPACHEKDM4EALDH1A1 | |
| SCHEMBL14256444 | 0.82 | MERTK (0.53) | APPACHEMERTKBCHECTNNB1 | |
| SCHEMBL14412248 | 0.82 | APP (0.45) | APPACHEMERTKBCHECTNNB1 | |
| SCHEMBL14256699 | 0.81 | MERTK (0.52) | APPACHEMERTKBCHECTNNB1 | |
| SCHEMBL14256861 | 0.81 | IRAK4 (0.40) | APPACHEMERTKBCHEIRAK4 | |
| SCHEMBL14256725 | 0.79 | IRAK4 (0.52) | APPACHEIRAK4KDRAURKB | |
| SCHEMBL14256740 | 0.78 | KMT2A (0.37) | APPACHEBCHERAD52KDM4E | |
| SCHEMBL14412272 | 0.78 | CXCR4 (0.52) | APPACHEMERTKBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081978-A2 | MODULATORS OF HEPATOCYTE GROWTH FACTOR / C-MET ACTIVITY | ANGION BIOMEDICA CORPORATION (US) | 2007-07-19 | — | — | WO | disclosed |