SCHEMBL1446791

SCHEMBL1446791

CC(C)(C)C(C)(Cc1ccccc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.53
HIF1A Q16665 1/20 0.53
SLC6A2 P23975 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.45
CYP2D6 P10635 1/20 0.45
TRPA1 O75762 1/20 0.44
MMP8 P22894 4/20 0.44
CYP1A2 P05177 2/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.43
MAPK1 P28482 1/20 0.42
FDPS P14324 1/20 0.42
CES2 O00748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28105527 0.86 SMN1; SMN2 (0.47) SMN1; SMN2HIF1ASLC6A2TAAR1PPARG
SCHEMBL16321813 0.84 SMN1; SMN2 (0.50) SMN1; SMN2HIF1ASLC6A2TAAR1PPARG
SCHEMBL28732435 0.80 ALDH1A1 (0.47) SMN1; SMN2HIF1AALDH1A1MAPK1FDPS
SCHEMBL28712409 0.79 SMN1; SMN2 (0.42) SMN1; SMN2HIF1ASLC6A2TAAR1PPARG
SCHEMBL5360398 0.79 SMN1; SMN2 (0.53) SMN1; SMN2HIF1ASLC6A2TAAR1PPARG
SCHEMBL517462 0.78 SMN1; SMN2 (0.57) SMN1; SMN2HIF1ASLC6A2TAAR1PPARG
SCHEMBL8710382 0.78 SMN1; SMN2 (0.57) SMN1; SMN2HIF1ASLC6A2TAAR1PPARG
SCHEMBL27908890 0.78 SMN1; SMN2 (0.57) SMN1; SMN2HIF1ASLC6A2TAAR1PPARG
SCHEMBL21269695 0.78 HIF1A (0.52) SMN1; SMN2HIF1ASLC6A2TAAR1PPARG
SCHEMBL21269112 0.78 HIF1A (0.52) SMN1; SMN2HIF1ASLC6A2TAAR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11179310-B2 Fragrance compositions and products with mood enhancing effects SYMRISE AG (DE) 2021-11-23 US claimed
EP-3621577-B1 NOVEL FRAGRANCE COMPOSITIONS AND PRODUCTS WITH MOOD ENHANCING EFFECTS SYMRISE AG (DE) 2021-06-30 EP claimed
US-20210077374-A1 NOVEL FRAGRANCE COMPOSITIONS AND PRODUCTS WITH MOOD ENHANCING EFFECTS KENVUE BRANDS LLC 2021-03-18 US claimed
EP-3621577-A1 NOVEL FRAGRANCE COMPOSITIONS AND PRODUCTS WITH MOOD ENHANCING EFFECTS Symrise AG (DE) 2020-03-18 EP claimed
WO-2018206297-A1 NOVEL FRAGRANCE COMPOSITIONS AND PRODUCTS WITH MOOD ENHANCING EFFECTS SYMRISE AG (DE) 2018-11-15 WO claimed
EP-1898865-B1 FRAGANCE COMPOSITIONS GIVAUDAN NEDERLAND SERVICES B (NL) 2010-04-21 EP claimed
EP-1928992-A1 CONSUMER PRODUCTS HAVING VARYING ODORS Henkel AG & Co. KGaA (DE) 2008-06-11 EP claimed
EP-1922398-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-21 EP claimed
EP-1835812-A2 GLYCOPYRROLATE IN COSMETIC PREPARATIONS Beiersdorf AG (DE) 2007-09-26 EP claimed
WO-2006069998-A9 GLYCOPYRROLATE IN COSMETIC PREPARATIONS BEIERSDORF AG (DE) 2007-08-23 WO claimed
WO-2007028477-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO claimed
WO-2007028479-A1 CONSUMER PRODUCTS HAVING VARYING ODORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO claimed
EP-1343466-B1 PERFUME COMPOSITIONS QUEST INT SERV BV (NL) 2007-01-03 EP claimed
WO-2006069998-A2 GLYCOPYRROLATE IN COSMETIC PREPARATIONS BEIERSDORF AG (DE) 2006-07-06 WO claimed
EP-2662434-B2 Use of specific compounds for enhancing odours SYMRISE AG (DE) 2023-08-16 EP disclosed
US-11179310-B2 Fragrance compositions and products with mood enhancing effects SYMRISE AG (DE) 2021-11-23 US disclosed
EP-2145042-B2 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2021-10-06 EP disclosed
EP-0010142-B1 SESQUITERPENOID TETRAHYDROFURAN DERIVATIVES (I) AS ISOLATED COMPOUNDS OR IN THE FORM OF MIXTURES, PROCESS AND STARTING MATERIALS (V) FOR THEIR PREPARATION, APPLICATION OF (I) AS PERFUMES AND/OR FLAVORS AND PERFUME AND/OR FLAVOR COMPOSITIONS WITH AN AMOUNT OF (I) L. Givaudan & Cie Société Anonyme (CH) 1981-07-22 EP disclosed
EP-0010142-A1 Sesquiterpenoid tetrahydrofuran derivatives (I) as isolated compounds or in the form of mixtures, process and starting materials (V) for their preparation, application of (I) as perfumes and/or flavors and perfume and/or flavor compositions with an amount of (I) L. Givaudan & Cie Société Anonyme (CH) 1980-04-30 EP disclosed
EP-0000771-A2 2,5,7-Trimethyloctane-3-ol and 2,4-dimethylnonane-8-ol; processes for their preparation; their use as olfactory agents; olfactory compositions containing them, as well as the preparation of such olfactory compositions L. Givaudan & Cie Société Anonyme (CH) 1979-02-21 EP disclosed