SCHEMBL14468

SCHEMBL14468

O=C1c2ccccc2C(=O)N1CCCCBr

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
MAPT P10636 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
GLS O94925 1/20 0.55
CYP1A2 P05177 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP2D6 P10635 1/20 0.54
MEN1 O00255 1/20 0.54
CHRM2 P08172 1/20 0.54
KMT2A Q03164 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC4 P56524 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
HDAC8 Q9BY41 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459467 1.00 TDP1 (0.61) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL585441 0.98 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19MEN1
SCHEMBL6561802 0.98 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19MEN1
SCHEMBL4579395 0.98 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19MEN1
SCHEMBL4580702 0.98 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19MEN1
SCHEMBL4579011 0.98 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19MEN1
SCHEMBL7515272 0.98 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19MEN1
SCHEMBL876407 0.98 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19MEN1
SCHEMBL3986297 0.98 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19MEN1
SCHEMBL98805 0.98 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2355 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406031-A Non-washing fluorescent probe containing azide group and preparation method and application thereof 河南大学 2024-07-30 CN claimed
CN-115887376-B Harmine modified medicine, preparation method and application 苏州大学 2024-07-09 CN claimed
CN-118221620-A Benzamide phenylpiperazine radioactive compound and preparation method and application thereof 中国科学院高能物理研究所 2024-06-21 CN claimed
CN-113072611-B Preparation method of glycyrrhetinic acid modified polypyridine ruthenium complex antibacterial agent 江西科技师范大学 2024-02-06 CN claimed
CN-116514858-A Harmel alkaloid derivative, preparation method and application thereof 苏州大学 2023-08-01 CN claimed
CN-115887376-A Harmine modified drug, preparation method and application 苏州大学 2023-04-04 CN claimed
CN-113754630-B Synthetic method of alpha-lipoic acid 苏州富士莱医药股份有限公司 2022-07-08 CN claimed
CN-113754630-A Synthetic method of alpha-lipoic acid 苏州富士莱医药股份有限公司 2021-12-07 CN claimed
CN-113072611-A Glycyrrhetinic acid modified polypyridyl ruthenium complex and preparation method and application thereof 江西科技师范大学 2021-07-06 CN claimed
CN-110016104-B Photo-stimulation response polyacrylamide self-repairing supramolecular hydrogel and preparation method thereof 华东师范大学 2021-05-25 CN claimed
WO-1997039894-A1 HEAT-SENSITIVE COMPOSITION AND METHOD OF MAKING A LITHOGRAPHIC PRINTING FORM WITH IT HORSELL GRAPHIC INDUSTRIES LIMITED (GB) 1997-10-30 WO claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0220409-B1 GEM-DIHALO AND TETRAHALO-1,12-DIAMINO-4,9-DIAZA-DODECANES MERRELL DOW PHARMACEUTICALS INC. (US) 1991-11-27 EP claimed
EP-0215319-B1 GEM-DIHALO-1,8-DIAMINO-4-AZA-OCTANES MERRELL DOW PHARMACEUTICALS INC. (US) 1991-10-16 EP claimed
US-4914240-A PROTECTING DIHALO BUTANEDIOL, REACTING WITH POTASSIUM PHTHALIMINDE, DEPROTECTING; MULTISTEP MERRELL DOW PHARMACEUTICALS INC. (US) 1990-04-03 US claimed
EP-0220409-A2 Gem-dihalo and tetrahalo-1,12-diamino-4,9-diaza-dodecanes MERRELL DOW PHARMACEUTICALS INC. (US) 1987-05-06 EP claimed
EP-0215319-A2 Gem-dihalo-1,8-diamino-4-aza-octanes MERRELL DOW PHARMACEUTICALS INC. (US) 1987-03-25 EP claimed