SCHEMBL31129

SCHEMBL31129

O=C1c2ccccc2C(=O)N1CCCCCBr

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.64
▸ L3MBTL1 Q9Y468 1/20 0.64
▸ CHRM2 P08172 2/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ CYP1A2 P05177 1/20 0.57
▸ CYP2C19 P33261 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ HDAC8 Q9BY41 3/20 0.57
▸ HDAC3 O15379 2/20 0.57
▸ HDAC4 P56524 2/20 0.57
▸ HDAC1 Q13547 2/20 0.57
▸ HDAC7 Q8WUI4 2/20 0.57
▸ HDAC2 Q92769 2/20 0.57
▸ HDAC10 Q969S8 2/20 0.57
▸ HDAC11 Q96DB2 2/20 0.57
▸ HDAC6 Q9UBN7 2/20 0.57
▸ HDAC9 Q9UKV0 2/20 0.57
▸ HDAC5 Q9UQL6 2/20 0.57
▸ ACHE P22303 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561802 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL4579301 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL585441 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL875645 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL31217 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL7523852 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL3468761 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL4580141 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL875710 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL876407 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429386-B Synthetic method of R-lipoic acid 苏州富士莱医药股份有限公司 2022-03-18 — — CN claimed
CN-113429386-A Synthetic method of R-lipoic acid 苏州富士莱医药股份有限公司 2021-09-24 — — CN claimed
JP-11035529-A — — None — — JP disclosed
EP-4747248-A1 COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION Institute of Cancer Research: Royal Cancer Hospital (The) (GB) 2026-05-27 — — EP disclosed
EP-4747260-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 — — EP disclosed
US-12606543-B2 Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto MINDSET PHARMA INC. (CA) 2026-04-21 — — US disclosed
EP-4704915-A1 LINKERS FOR DRUG CONJUGATES AND ANTIBODY DRUG CONJUGATES BioAtla, Inc. (US) 2026-03-11 — — EP disclosed
US-12502434-B2 Compound comprising EZH2 inhibitor and E3 ligase binder and pharmaceutical composition for preventing or treating EZH2-associated disease comprising same as active ingredient DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2025-12-23 — — US disclosed
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-10-23 — — US disclosed
US-20250325491-A1 POLYVALENT MOLECULE BASED LIPID NANOPARTICLES FOR NUCLEIC ACID DELIVERY BIO TRIP B V (NL) 2025-10-23 — — US disclosed
EP-4613773-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-10 — — EP disclosed
EP-0087853-A2 4-Diphenylmethyl-1-(oxoalkyl)imino)methyl-piperidines and their derivatives McNeilab, Inc. (US) 1983-09-07 — — EP disclosed
US-4374829-A Aminoacid derivatives as antihypertensives MERCK & CO., INC. (US) 1983-02-22 — — US disclosed
US-4370335-A Antisecretory 4-diphenylmethyl-1-[(oxoalkyl)imino]methyl-piperidines and their derivatives MCNEILAB, INC. (US) 1983-01-25 — — US disclosed
US-4363808-A N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines BERLEX LABORATORIES, INC. (US) 1982-12-14 — — US disclosed
EP-0043285-A1 Method for determination of valproic acid and reagents therein Dainippon Pharmaceutical Co., Ltd. (JP) 1982-01-06 — — EP disclosed
EP-0029306-A1 Aminoalkyl compounds, their production and pharmaceutical compositions containing them GLAXO GROUP LIMITED (GB) 1981-05-27 — — EP disclosed
WO-1980001685-A1 RADIOLABELED AMINE COMPOUNDS AND THEIR USE BYK MALLINCKRODT CIL BV (NL) 1980-08-21 — — WO disclosed
EP-0012401-A1 Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them MERCK & CO. INC. (US) 1980-06-25 — — EP disclosed
US-4167638-A Process for production of 8-NHR quinolines THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1979-09-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 TDP1 236/4885L3MBTL1 1394/4885CHRM2 4681/4885
US-12502434-B2 Compound comprising EZH2 inhibitor and E3 ligase binder and pharmaceutical composition for preventing or treating EZH2-associated disease comprising same as active ingredient EZH2, BMI1, SUZ12 TDP1 3035/4885L3MBTL1 886/4885CHRM2 4736/4885
US-20250325491-A1 POLYVALENT MOLECULE BASED LIPID NANOPARTICLES FOR NUCLEIC ACID DELIVERY POLRMT, TLR3, TLR9 TDP1 1129/4885L3MBTL1 214/4885CHRM2 4867/4885
US-12606543-B2 Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto HTR6, CNR1, HTR3C TDP1 2032/4885L3MBTL1 2027/4885CHRM2 74/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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