Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.39 |
| ▸ | GMNN | O75496 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | UBE2N | P61088 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | THPO | P40225 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27989508 | 0.92 | LMNA (0.41) | LMNAL3MBTL1TDP1CYP2D6MAPT | |
| SCHEMBL18398907 | 0.83 | LMNA (0.59) | LMNAL3MBTL1TDP1CYP2D6MAPT | |
| SCHEMBL18398906 | 0.83 | LMNA (0.59) | LMNAL3MBTL1TDP1CYP2D6MAPT | |
| SCHEMBL9669465 | 0.83 | LMNA (0.59) | LMNAL3MBTL1TDP1CYP2D6MAPT | |
| SCHEMBL8528304 | 0.81 | LMNA (0.65) | LMNAL3MBTL1TDP1CYP2D6MAPT | |
| SCHEMBL2463563 | 0.81 | LMNA (0.65) | LMNAL3MBTL1TDP1CYP2D6MAPT | |
| SCHEMBL19352395 | 0.81 | — | — | |
| SCHEMBL11146359 | 0.81 | — | — | |
| SCHEMBL12601084 | 0.81 | — | — | |
| SCHEMBL2463562 | 0.81 | LMNA (0.65) | LMNAL3MBTL1TDP1CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173787-A1 | Thin-film nitinol based drug eluting stent | CORDIS US CORP | 2007-07-26 | — | — | US | disclosed |