SCHEMBL2463563

SCHEMBL2463563

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nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
TDP1 Q9NUW8 1/20 0.61
USP2 O75604 1/20 0.52
SLCO1B1 Q9Y6L6 1/20 0.52
KDM4E B2RXH2 3/20 0.44
PDE4A P27815 1/20 0.44
CYP2D6 P10635 2/20 0.38
MAPT P10636 2/20 0.38
SPHK1 Q9NYA1 1/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CETP P11597 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528432 1.00 LMNA (0.65) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL8528496 1.00 LMNA (0.65) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL2463562 1.00 LMNA (0.65) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL3797037 1.00 LMNA (0.65) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL8528304 1.00 LMNA (0.65) LMNAL3MBTL1TDP1USP2SLCO1B1
Hydrochloric Acid SCHEMBL9147289 0.97 LMNA (0.61) LMNAL3MBTL1TDP1USP2SLCO1B1
Hydrochloric Acid SCHEMBL9147272 0.97 LMNA (0.61) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL9669465 0.91 LMNA (0.59) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL18398907 0.91 LMNA (0.59) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL18398906 0.91 LMNA (0.59) LMNAL3MBTL1TDP1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020162-A Polypropylene material with high melt strength and low shrinkage and preparation method thereof 中国石油天然气股份有限公司 2025-05-20 CN claimed
EP-2369947-B1 BEER AND BEER-BASED BEVERAGES AND METHOD OF MODIFICATION OF POLYPHENOLS AND SILICON CONTENT IN THESE BEVERAGES AGRA GROUP AS (CZ) 2013-03-06 EP claimed
CN-102600063-A Method for preparing curcumin micelle with high medicine loading UNIV TIANJIN 2012-07-25 CN claimed
US-20110256298-A1 BEER AND BEER-BASED BEVERAGES AND METHOD OF MODIFICATION OF POLYPHENOLS AND SILICON CONTENT IN THESE BEVERAGES AGRA GROUP, A.S. (CZ) 2011-10-20 US claimed
EP-2369947-A2 BEER AND BEER-BASED BEVERAGES AND METHOD OF MODIFICATION OF POLYPHENOLS AND SILICON CONTENT IN THESE BEVERAGES Agra Group, A.S. (CZ) 2011-10-05 EP claimed
WO-2010072183-A2 BEER AND BEER-BASED BEVERAGES AND METHOD OF MODIFICATION OF POLYPHENOLS AND SILICON CONTENT IN THESE BEVERAGES AGRA GROUP, A.S. (CZ) 2010-07-01 WO claimed
EP-0998946-A1 Non-porphyrin compound for use as a diagnosticum and/or pharmaceutical K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) 2000-05-10 EP claimed
WO-2000009169-A1 NON-PORPHYRIN COMPOUND FOR USE AS A DIAGNOSTICUM AND/OR PHARMACEUTICAL K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) 2000-02-24 WO claimed
EP-0322571-B1 METHOD FOR MANUFACTURING 2-AMINO-2-DEOXY-D-MANNITOL NIPPON SHINYAKU COMPANY, LIMITED (JP) 1993-02-03 EP claimed
US-4894344-A CULTURE OF STREPTOMYCES OR MUTANTS NIPPON SHINYAKU CO., LTD. (JP) 1990-01-16 US claimed
EP-0322571-A1 Method for manufacturing 2-amino-2-deoxy-D-mannitol NIPPON SHINYAKU COMPANY, LIMITED (JP) 1989-07-05 EP claimed
US-4109081-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1978-08-22 US claimed
JP-2104288-A None JP disclosed
US-20250388615-A9 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS ARDELYX, INC. (US) 2025-12-25 US disclosed
CN-120020162-A Polypropylene material with high melt strength and low shrinkage and preparation method thereof 中国石油天然气股份有限公司 2025-05-20 CN disclosed
US-20250066410-A1 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS ARDELYX, INC. (US) 2025-02-27 US disclosed
EP-0240175-A1 Inosose derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1987-10-07 EP disclosed
US-4307072-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1981-12-22 US disclosed
US-4224440-A NON-IONIC X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1980-09-23 US disclosed
US-4109081-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1978-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066410-A1 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS GPR119, GIPR, GLP1R LMNA 4746/4885L3MBTL1 3620/4885TDP1 3907/4885
US-20250388615-A9 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS GPR119, GIPR, FFAR3 LMNA 4241/4885L3MBTL1 2649/4885TDP1 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.