Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23182183 | 0.96 | KDM4E (0.70) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL4512048 | 0.96 | KDM4E (0.70) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL5567542 | 0.90 | SCN4A (0.62) | KDM4EALDH1A1HPGDCYP2D6MEN1 | |
| SCHEMBL12174911 | 0.90 | SCN4A (0.62) | KDM4EALDH1A1HPGDCYP2D6MEN1 | |
| SCHEMBL12174984 | 0.90 | SCN4A (0.62) | KDM4EALDH1A1HPGDCYP2D6MEN1 | |
| SCHEMBL3844177 | 0.84 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL18125935 | 0.84 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL23182612 | 0.83 | S1PR5 (0.66) | KDM4EALDH1A1HPGD | |
| SCHEMBL3063205 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL22098367 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1HPGDCYP2D6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241887-B2 | 3-azabicyclo[3.2.1]octane derivatives | PFIZER INC (US) | 2007-07-10 | — | — | US | disclosed |